Sterile Corneal Infiltrates Secondary to Psoriasis Exacerbations: Topical Tacrolimus as an Alternative Treatment Option

Psoriasis is a common chronic inflammatory skin disease. Ocular manifestations, which occur in 10% to 20% of cases of psoriasis, are usually bilateral and often present during an exacerbation of the psoriasis. Serious corneal involvement is rare but can be devastating. Two cases of sterile corneal i...

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Bibliographic Details
Published inEye & contact lens Vol. 43; no. 1; p. e1
Main Authors Gonzalez-Andrades, Miguel, Arias-Santiago, Salvador, García-Serrano, José Luis, González Gallardo, María Del Carmen, McAlinden, Colm
Format Journal Article
LanguageEnglish
Published United States 01.01.2017
Subjects
Administration, Topical
Adult
Corneal Diseases - drug therapy
Corneal Diseases - etiology
Humans
Immunosuppressive Agents - therapeutic use
Male
Ointments
Psoriasis - complications
Psoriasis - drug therapy
Tacrolimus - therapeutic use
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Summary:Psoriasis is a common chronic inflammatory skin disease. Ocular manifestations, which occur in 10% to 20% of cases of psoriasis, are usually bilateral and often present during an exacerbation of the psoriasis. Serious corneal involvement is rare but can be devastating. Two cases of sterile corneal infiltrates secondary to an exacerbation of psoriasis are presented. Treatment involved the use of 0.02% topical tacrolimus ointment, which resulted in resolution of the symptoms and infiltrates. Topical tacrolimus may be considered as an alternative treatment option to corticosteroids in sterile corneal infiltrates.
ISSN:1542-233X
DOI:10.1097/ICL.0000000000000178