Delayed Norfentanyl Clearance During Pregnancy

• Published in: Obstetrics and gynecology (New York. 1953) Vol. 136; no. 5; pp. 905 - 907
• Main Authors: Wanar, Amita, Saia, Kelley, Field, Thomas A
• Format: Journal Article
• Language: English
• Published: United States by The American College of Obstetricians and Gynecologists. Published by Wolters Kluwer Health, Inc. All rights reserved 01.11.2020
• Subjects: Adult; Analgesics, Opioid - pharmacokinetics; Female; Fentanyl - analogs & derivatives; Fentanyl - pharmacokinetics; Fentanyl - urine; Humans; Metabolic Clearance Rate; Opioid-Related Disorders - urine; Pregnancy; Pregnancy Complications - urine

BACKGROUND:We report a case of delayed norfentanyl clearance in a 33-year-old pregnant woman. Norfentanyl is the major metabolite of fentanyl. CASE:A multigravid woman with opioid use disorder presented at 7 weeks of gestation for treatment. Despite opioid abstinence, her urine was positive for norf...