Fluctuating Posterior Canal Function in Benign Paroxysmal Positional Vertigo Depending on How and Where Otoconia Are Disposed

• Published in: Otology & neurotology Vol. 42; no. 2; p. e193
• Main Authors: Castellucci, Andrea, Malara, Pasquale, Martellucci, Salvatore, Delmonte, Silvia, Ghidini, Angelo
• Format: Journal Article
• Language: English
• Published: United States 01.02.2021
• Subjects: Benign Paroxysmal Positional Vertigo; Female; Humans; Middle Aged; Nystagmus, Pathologic; Nystagmus, Physiologic; Otolithic Membrane; Semicircular Canals - diagnostic imaging
• ISSN: 1537-4505
• DOI: 10.1097/MAO.0000000000002913

Though fluctuations in vestibular function represent a common finding in Menière's disease, we describe how benign paroxysmal positional vertigo (BPPV) may result in fluctuations of vestibulo-ocular reflex for the involved canal depending on the disposition of otoliths. A 54-year-old woman suffering from refractory posterior canal (PC)-BPPV resulting in fluctuating PC function. Diagnostic evaluation and rehabilitative treatment for BPPV involving the affected PC. Video-Frenzel and video-head impulse test (vHIT) findings before and after canalith repositioning procedures for PC-BPPV. BPPV involving the nonampullary arm of right PC was diagnosed based on presenting positional downbeat nystagmus and selective right PC hypofunction at the vHIT. During physical treatment, nystagmus first became positional paroxysmal upbeat likely due to a shift of debris into the ampullary arm of the canal, then turned to spontaneous downbeat nystagmus consistently with a plug effect exerted by particles entrapped within the nonampullary arm of PC and finally receded proving an otoliths fall within the utriculus. Simultaneously, vHIT documented fluctuations for right PC vestibulo-ocular reflex gain as it first increased to normal values, then severely declined and finally normalized, respectively. High-resolution computed tomography scan detected ipsilateral superior canal dehiscence. In accordance with recently reported vHIT findings in different types of BPPV, fluctuation of PC function could be likely explained by the effect of particles on cupular dynamic responses depending on the portion of the canal gradually involved. Superior canal dehiscence may have played a role facilitating otoliths mobilization by reducing labyrinthine impedance.