Emerging Role of Long Non‑coding RNAs in Asthma

Asthma is a common complex disorder characterized by hyper-responsiveness and chronic inflammatory airway disease in children and adults worldwide. The prevalence of asthma is increasing with each passing year. Long non-coding RNAs (lncRNAs), regarded as a potentially promising path, have received i...

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Bibliographic Details
Published inCombinatorial chemistry & high throughput screening Vol. 26; no. 2; p. 247
Main Authors Chen, Xue-Fen, Deng, Jing-Min
Format Journal Article
LanguageEnglish
Published United Arab Emirates 01.01.2023
Subjects
Adult
Asthma - diagnosis
Asthma - genetics
Child
Humans
Pulmonary Disease, Chronic Obstructive
RNA, Long Noncoding - genetics
chromation
molecular mechanism
long non‑coding RNA
therapeutic target
biomarker
Asthma
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Summary:Asthma is a common complex disorder characterized by hyper-responsiveness and chronic inflammatory airway disease in children and adults worldwide. The prevalence of asthma is increasing with each passing year. Long non-coding RNAs (lncRNAs), regarded as a potentially promising path, have received increasing attention in exploring the biological regulation of chronic airway diseases, although they have no or limited protein-coding capacity. This review highlights the functional roles and clinical significance of lncRNAs in the pathogenesis of asthma and provides directions for diagnosing and treating asthma in the future.
ISSN:1875-5402
DOI:10.2174/1386207325666220825152237