1,3,4-Triarylpyrazoles Containing 2-Thioxoimidazolidinones and Different Fused Systems: Synthesis and Antimicrobial Activity

A group of new analogs of 1,3,4-trisubstituted pyrazoles functionalized 2-thioxoimidazolidinones and fused heterocyclic systems are synthesized. Their tests of antimicrobial activity against several bacterial and fungal strains indicated relatively high activity. The composition of the novel product...

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Bibliographic Details
Published inRussian journal of general chemistry Vol. 88; no. 12; pp. 2646 - 2652
Main Authors Khalifa, N. M., El-Sayed, A. S., Abd El-Karim, S. S., Hassan, E. S., Nossier, E. S., Shalaby, A. G.
Format Journal Article
LanguageEnglish
Published Moscow Pleiades Publishing 01.12.2018
Springer Nature
Springer
Springer Nature B.V
Subjects
Antiinfectives and antibacterials
Antimicrobial agents
Chemistry
Chemistry and Materials Science
Chemistry, Multidisciplinary
Chemistry/Food Science
Heterocyclic compounds
Physical Sciences
Science & Technology
synthesis
1,3,4-trisubstituted pyrazoles
antimicrobial activity
PYRAZOLE
AGENTS
INHIBITORS
DERIVATIVES
ANTITUMOR
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Summary:A group of new analogs of 1,3,4-trisubstituted pyrazoles functionalized 2-thioxoimidazolidinones and fused heterocyclic systems are synthesized. Their tests of antimicrobial activity against several bacterial and fungal strains indicated relatively high activity. The composition of the novel products was elucidated from spectroscopic data.
ISSN:1070-3632
1608-3350
DOI:10.1134/S1070363218120277