Fist-Palm Test (FiPaT): a bedside motor tool to screen for global cognitive status

• Published in: Neurological sciences Vol. 43; no. 9; pp. 5251 - 5258
• Main Authors: Cuoco, Sofia, Erro, Roberto, Carotenuto, Immacolata, Picillo, Marina, Pellecchia, Maria Teresa, Barone, Paolo
• Format: Journal Article
• Language: English
• Published: Cham Springer International Publishing 01.09.2022; Springer Nature B.V
• Subjects: Aged; Cognition; Cognitive ability; Cognitive Dysfunction - diagnosis; Cognitive Dysfunction - psychology; Executive Function; Humans; Medicine; Medicine & Public Health; Middle Aged; Neurology; Neuropsychological Tests; Neuropsychology; Neuroradiology; Neurosciences; Neurosurgery; Original; Original Article; Psychiatry; Reproducibility of Results; Normal cognition; Cognitive screening; Mild cognitive impairment; Non-verbal test
• ISSN: 1590-1874; 1590-3478; 1590-3478
• DOI: 10.1007/s10072-022-06129-1

Objective The Fist-Palm Test (FiPaT) is a novel non-verbal task to be used at the patient’s bedside for a cognitive functions screening. The aims of this study are to analyze (I) the qualitative and quantitative performance features at FiPaT, (II) the psychometric characteristics of FiPaT, and (III) the correlation between FiPat and traditional cognitive assessments in subjects with normal cognition (NC), Mild Cognitive Impairment-single domain (MCI-sd), and Mild Cognitive Impairment-multiple domain (MCI-md). Methods One hundred-thirteen subjects (53M/60F), with a mean age of 66.28 ± 7.22 years and 11.08 ± 4.93 years of education, were recruited and underwent a complete neuropsychological battery and FiPaT. Results We found 68 subjects with NC, 31 with MCI-sd, and 14 with MCI-md and a high reliability of the FiPaT (alpha =0.762). The number of FiPaT errors correlated with age and all neuropsychological tests, except for the memory recall test. Subjects with MCI had greater FiPaT errors than subjects with NC. The FiPaT, used with the MOCA test, predicted the presence of MCI, with a variance of 44%. Conclusion The FiPaT is an acceptable and reliable non-verbal test, able to screen for global cognitive status, attention, and executive functions, and to predict the MCI. Future studies will validate this initial findings as well as the discriminatory role of the FiPaT in detecting specific types of cognitive impairment.