Synthesis, Structure, and Properties of 2-Oxo-3-formylquinolone Acylhydrazone Containing a Trimethylammonium Fragment and also of Transition Metal Complexes Based on This Compound

• Published in: Russian journal of general chemistry Vol. 92; no. 12; pp. 2796 - 2808
• Main Authors: Popov, L. D., Tupolova, Yu. P., Vlasenko, V. G., Borodkin, S. A., Levchenkov, S. I., Lebedev, V. E., Askalepova, O. I., Borodkin, G. S., Zubenko, A. A., Gishko, K. B., Zubavichus, Ya. V., Lazarenko, V. A., Shcherbakov, I. N.
• Format: Journal Article
• Language: English
• Published: Moscow Pleiades Publishing 01.12.2022; Springer; Springer Nature B.V
• Subjects: Chemistry; Chemistry and Materials Science; Chemistry/Food Science; Condensates; Coordination compounds; Copper; Hydrazones; Nickel; Synthesis; Transition metal compounds; Zinc; metal complexes; biological activity; X-ray absorption spectroscopy; hydrazones; X-ray diffraction analysis
• ISSN: 1070-3632; 1608-3350
• DOI: 10.1134/S1070363222120301

The product of 3-formyl-2-quinolone condensation with trimethylammonium chloride acethydrazide, (H 2 L + )Сl – hydrazone, was synthesized. Complexes of Zn(II) and Cu(II), [M(HL)OCH 3 ]ClO 4 , with a distorted square-planar strucrure of coordination sites and asymmetric chelate сomplexes of Mn(II), Ni(II), and Co(II), [M(HL)(H 2 L)]·(ClO 4 ) 3 , of pseudo-octahedral structure were obtained on its basis. The protistocidal, antibacterial, and fungistatic activities of the synthesized compounds were studied.