Treatment of rheumatoid arthritis by phototherapy: advances and perspectives

Rheumatoid arthritis (RA) is an inflammatory disease that is prevalent worldwide and seriously threatens human health. Though traditional drug therapy can alleviate RA symptoms and slow progression, high dosage and frequent administration would cause unfavorable side effects. Phototherapy including...

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Bibliographic Details
Published inNanoscale Vol. 13; no. 35; pp. 14591 - 1468
Main Authors Dong, Yunxia, Cao, Wei, Cao, Jie
Format Journal Article
LanguageEnglish
Published Cambridge Royal Society of Chemistry 17.09.2021
Subjects
Apoptosis
Arthritis
Chemotherapy
Light irradiation
Light therapy
Necrosis
Photodynamic therapy
Rheumatoid arthritis
Side effects
Signs and symptoms
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Summary:Rheumatoid arthritis (RA) is an inflammatory disease that is prevalent worldwide and seriously threatens human health. Though traditional drug therapy can alleviate RA symptoms and slow progression, high dosage and frequent administration would cause unfavorable side effects. Phototherapy including photodynamic therapy (PDT) and photothermal therapy (PTT) has demonstrated distinctive potential in RA treatment. Under light irradiation, phototherapy can convert light into heat, or generate ROS, to promote necrosis or apoptosis of RA inflammatory cells, thus reducing the concentration of related inflammatory factors and relieving the symptoms of RA. In this review, we will summarize the development in the application of phototherapy in the treatment of rheumatoid arthritis. In this review, we summarized the development in the application of phototherapy in the treatment of rheumatoid arthritis.
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ISSN:2040-3364
2040-3372
DOI:10.1039/d1nr03623h