Challenges in studying phospholipid signaling

Because of the large number of phospholipids, their highly active metabolism and our lack of understanding of protein-lipid specificity, lipid signaling is a particularly challenging subject to study. Help might come from new tools that will allow us to follow and manipulate lipids and lipid-binding...

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Bibliographic Details
Published inNature chemical biology Vol. 6; no. 7; pp. 473 - 475
Main Author Schultz, Carsten
Format Journal Article
LanguageEnglish
Published New York Nature Publishing Group US 01.07.2010
Nature Publishing Group
Subjects
631/80/86/2365
631/92/287/1194
631/92/96
Biochemical Engineering
Biochemistry
Bioorganic Chemistry
Cell adhesion & migration
Cell Biology
Chemistry
Chemistry and Materials Science
Chemistry/Food Science
commentary
Humans
Lipid Metabolism - physiology
Lipids
Phospholipids - metabolism
Protein Binding
Proteins
Proteins - metabolism
Signal Transduction - physiology
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Summary:Because of the large number of phospholipids, their highly active metabolism and our lack of understanding of protein-lipid specificity, lipid signaling is a particularly challenging subject to study. Help might come from new tools that will allow us to follow and manipulate lipids and lipid-binding proteins in living cells.
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ISSN:1552-4450
1552-4469
1552-4469
DOI:10.1038/nchembio.389