Synthesis and Antibacterial Activity of 3,6-Diaryl-7H-[1,2,4]Triazolo[3,4-b][1,3,4]Thiadiazines

Interaction of 4-amino-5-(2-alkoxyphenyl)-4 H -[1,2,4]triazole-3-thiols with substituted phenacyl bromides was used to synthesize 6-(2′-alkoxyphenyl)-3-aryl-7 H -[1,2,4]triazolo[3,4- b ][1,3,4]thiadiazines. Biological studies identified an interaction between chemical structure and antibacterial act...

Full description

Saved in:
Bibliographic Details
Published inPharmaceutical chemistry journal Vol. 50; no. 1; pp. 10 - 15
Main Authors Iradyan, M. A., Iradyan, N. S., Minasyan, N. S., Paronikyan, R. V., Stepanyan, G. M.
Format Journal Article
LanguageEnglish
Published New York Springer US 01.04.2016
Springer
Subjects
Antibacterial agents
Medicine
Organic Chemistry
Pharmacology/Toxicology
Pharmacy
Resveratrol
Search for New Drugs
synthesis
antibacterial activity
triazolothiadiazines
Online AccessGet full text

Cover

More Information
Summary:Interaction of 4-amino-5-(2-alkoxyphenyl)-4 H -[1,2,4]triazole-3-thiols with substituted phenacyl bromides was used to synthesize 6-(2′-alkoxyphenyl)-3-aryl-7 H -[1,2,4]triazolo[3,4- b ][1,3,4]thiadiazines. Biological studies identified an interaction between chemical structure and antibacterial activity in this series of triazolothiadiazines.
ISSN:0091-150X
1573-9031
DOI:10.1007/s11094-016-1389-y