Metastatic myxofibrosarcoma of the spermatic cord responding to mesna, adriamycin, ifosfamide, and dacarbazine combination therapy

Myxofibrosarcoma is common in the extremities of elderly people and is characterized by a high frequency of local recurrence. We report herein a case of a 72-year-old male who presented with a 5-year history of right scrotal swelling and a month history of painful swelling in the scrotal area. Compu...

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Bibliographic Details
Published inInternational cancer conference journal Vol. 1; no. 2; pp. 79 - 82
Main Authors Ito, Hideaki, Oyama, Nobuyuki, Miwa, Yoshiji, Akino, Hironobu, Imamura, Yoshiaki, Yokoyama, Osamu
Format Journal Article
LanguageEnglish
Published Japan Springer Japan 01.04.2012
Springer Nature B.V
Subjects
Cancer therapies
Case Report
Case reports
Chemotherapy
Computed tomography
Conflicts of interest
Dacarbazine
Ifosfamide
Lymph nodes
Lymphatic system
Medical imaging
Medicine
Medicine & Public Health
Metastases
Metastasis
Oncology
Patients
Rectum
Remission
Sarcoma
Scandals
Smooth muscle
Spermatic cord
Surgery
Surgical Oncology
Tumors
MAID
Spermatic cord
Myxofibrosarcoma
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Summary:Myxofibrosarcoma is common in the extremities of elderly people and is characterized by a high frequency of local recurrence. We report herein a case of a 72-year-old male who presented with a 5-year history of right scrotal swelling and a month history of painful swelling in the scrotal area. Computed tomography scan revealed a scrotal tumor 5 cm in size and a tumor in the rectum. He subsequently underwent right high orchiectomy and rectal dissection with colostomy. The scrotal tumor was histopathologically diagnosed as a myxofibrosarcoma; the rectal tumor was a leiomyosarcoma. The patient underwent tumor resection for recurrence and left inguinal metastasis, but soon developed local recurrences and lymph node metastasis of the left iliac area. Chemotherapy with mesna, adriamycin, ifosfamide, and dacarbazine (MAID) resulted in partial remission. We report the rare case of myxofibrosarcoma in the spermatic cord for which chemotherapy with MAID was an effective treatment.
ISSN:2192-3183
2192-3183
DOI:10.1007/s13691-011-0015-9