Efficient Synthesis and Reactions of New Functionally Substituted Pyrido[2,3-d]pyrimidine Candidates

Pyrido[2,3- d ]pyrimidine derivatives were synthesized by the reaction of 2-hydrazinopyrido[2,3- d ]-pyrimidin-4(3 H )-one with different aryl aldehydes and active methylene compounds. Their structures were characterized by spectroscopic methods.

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Bibliographic Details
Published inRussian journal of general chemistry Vol. 88; no. 6; pp. 1228 - 1231
Main Authors Khalifa, N. M., Nossier, E. S., Amr, A. E.
Format Journal Article
LanguageEnglish
Published Moscow Pleiades Publishing 01.06.2018
Springer Nature
Springer
Springer Nature B.V
Subjects
Aldehydes
Aromatic compounds
Chemical synthesis
Chemistry
Chemistry and Materials Science
Chemistry, Multidisciplinary
Chemistry/Food Science
Physical Sciences
Pyrimidines
Schiff bases
Science & Technology
pyrido[2,3
hydrazide-hydrazone
Schiff base derivatives
pyrimidines
DESIGN
BIOLOGICAL EVALUATION
pyrido[2,3-d]pyrimidines
ANTITUMOR-ACTIVITY
DERIVATIVES
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Summary:Pyrido[2,3- d ]pyrimidine derivatives were synthesized by the reaction of 2-hydrazinopyrido[2,3- d ]-pyrimidin-4(3 H )-one with different aryl aldehydes and active methylene compounds. Their structures were characterized by spectroscopic methods.
ISSN:1070-3632
1608-3350
DOI:10.1134/S1070363218060300