Cerebral atrophy: a schistosomiasis manifestation?

Preliminary studies with sonography indicated that a reduced brain mantle index and dilated ventricles were frequently seen in patients with chronic Schistosoma mansoni infection. Computerized tomography (CT) was used to confirm our earlier observations and to obtain more accurate measures. Brain sc...

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Bibliographic Details
Published inThe American journal of tropical medicine and hygiene Vol. 35; no. 3; p. 531
Main Authors Khalil, H H, Abd el Wahab, M, el Deeb, A, Ayad, W, Hamdy, E, Badawi, T, el Halawani, N, Khalil, T, Seddik, Z, Belal, A
Format Journal Article
LanguageEnglish
Published United States 01.05.1986
Subjects
Adolescent
Adult
Atrophy
Brain - diagnostic imaging
Brain - pathology
Cerebral Cortex - diagnostic imaging
Cerebral Cortex - pathology
Chronic Disease
Humans
Male
Schistosomiasis mansoni - diagnostic imaging
Schistosomiasis mansoni - pathology
Tomography, X-Ray Computed
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Summary:Preliminary studies with sonography indicated that a reduced brain mantle index and dilated ventricles were frequently seen in patients with chronic Schistosoma mansoni infection. Computerized tomography (CT) was used to confirm our earlier observations and to obtain more accurate measures. Brain scans of 25 patients with chronic S. mansoni infection showed mild to moderate degrees of cortical atrophy in 9 cases (36%) and central atrophy in 3 (12%). The remaining 16 subjects and 10 controls showed normal brain scans. The present study is the first report documented by CT showing a significant correlation between chronic S. mansoni infection and cerebral atrophy.
ISSN:0002-9637
DOI:10.4269/ajtmh.1986.35.531