The Impact of Directly Observed Therapy on Preventive Treatment for Latent Tuberculosis Infection among Students in Dalian, China

• Published in: Biomedical and environmental sciences Vol. 28; no. 8; pp. 611 - 615
• Main Authors: CHEN, Qi, WANG, Xue Mei, QI, Yi, LIU, Xiao Fang, JIANG, Li Ping, HOU, Wen, ZHOU, Ling, LU, Xi Wei
• Format: Journal Article
• Language: English
• Published: China Elsevier B.V 01.08.2015; Department of Public Health, Dalian Medical University, Dalian 116044, Liaoning, China%Department of Tuberculosis Prevention and Control, Tuberculosis Hospital of Dalian, Dalian 116033, Liaoning, China%College of Mathematics, Liaoning Normal University, Dalian 116029, Liaoning, China
• Subjects: Adult; Antitubercular Agents - therapeutic use; China; Directly Observed Therapy; Female; Humans; Latent Tuberculosis - drug therapy; Male; Patient Compliance; Young Adult; 临床; 环境科学; 生物医学; 诊断; China
• ISSN: 0895-3988; 2214-0190
• DOI: 10.3967/bes2015.085

Preventive treatment has an essential effect on latent tuberculosis infection （I.TBI） [purified protein derivative （PPD） induration 〉15 mml. Between 2010 and 2013, there were 6 tuberculosis （TB） outbreaks in the universities in Dalian, China. So far, in Dalian, the directly observed therapy （DOT） and full course management （FCM） were widely used in the preventive treatment of LTBI. However, it is yet to be determined which one of them has better efficacy. Therefore, the purpose of our study was to explore the performance of these two strategies for LTBI preventive treatment.