Subconjunctival masses associated with central nervous system rosai-dorfman disease

To describe a case of subconjunctival masses with multiple intracranial masses diagnosed as Rosai-Dorfman disease by biopsy. Case report. A 25-year-old white man presented with bilateral subconjunctival masses, left optic nerve pallor, and posterior segment changes suggestive of regressed choroidal...

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Bibliographic Details
Published inCornea Vol. 30; no. 2; p. 237
Main Authors Cavuoto, Kara, Galor, Anat, Dubovy, Sander R, Gregori, Ninel, McCarthy, Micheline
Format Journal Article
LanguageEnglish
Published United States 01.02.2011
Subjects
Administration, Oral
Adult
Brain Diseases - complications
Brain Diseases - diagnosis
Brain Diseases - drug therapy
Conjunctival Diseases - pathology
Conjunctival Diseases - surgery
Histiocytosis, Sinus - pathology
Humans
Injections, Intravenous
Magnetic Resonance Imaging
Male
Retrospective Studies
Seizures - etiology
Steroids - administration & dosage
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Summary:To describe a case of subconjunctival masses with multiple intracranial masses diagnosed as Rosai-Dorfman disease by biopsy. Case report. A 25-year-old white man presented with bilateral subconjunctival masses, left optic nerve pallor, and posterior segment changes suggestive of regressed choroidal disease. Systemic evaluation was instituted including blood testing, neuroimaging, brain biopsy, and biopsy of the left subconjunctival mass. Pathologic analysis of the brain and subconjunctival mass biopsies revealed Rosai-Dorfman disease. The authors present a case of extensive extranodal involvement of Rosai-Dorfman of the eye and the central nervous system.
ISSN:1536-4798
DOI:10.1097/ICO.0b013e3181e4570c