Silica-bonded S-Sulfonic Acid: A Recyclable Catalyst for the Synthesis of Trisubstituted Imidazoles under Solvent-free Conditions

• Published in: Chinese journal of chemistry Vol. 28; no. 4; pp. 663 - 669
• Main Authors: Niknam, Khodabakhsh, Mohammadizadeh, Mohammad R., Mirzaee, Salimeh, Saberi, Dariush
• Format: Journal Article
• Language: English
• Published: Weinheim WILEY-VCH Verlag 01.04.2010; WILEY‐VCH Verlag; Wiley; Wiley Subscription Services, Inc
• Subjects: aldehyde; catalyst; Chemistry; Chemistry, Multidisciplinary; Physical Sciences; Science & Technology; silica-bonded S-sulfonic acid; solvent-free; trisubstituted imidazole; ONE-POT SYNTHESIS; ACETYLATION; MICROWAVE; EFFICIENT SYNTHESIS; aldehyde; SULFURIC-ACID; solvent-free; ALCOHOLS; FORMYLATION; catalyst; silica-bonded S-sulfonic acid; 2,4,5-TRISUBSTITUTED IMIDAZOLES; trisubstituted imidazole; AEROBIC OXIDATION; QUINOXALINES
• ISSN: 1001-604X; 1614-7065
• DOI: 10.1002/cjoc.201090129

Trisubstituted imidazoles have been synthesized in high yields in the presence of silica‐bonded S‐sulfonic acid as a catalyst. The reaction was carried out at 130°C under solvent‐free conditions. The reaction work‐up is simple and the catalyst is easily separated from the products by filtration. Trisubstituted imidazoles have been synthesized in high yields in the presence of silica‐bonded S‐sulfonic acid as a catalyst. The reaction was carried out at 130°C under solvent‐free conditions.