Sorting and trafficking of ion transport proteins in polarized epithelial cells

Transport proteins are targeted to specific plasmalemmal domains in polarized epithelial cells. The molecular signals that govern these sorting events are just beginning to be elucidated. In many cases, the cell surface delivery of transport proteins is subjected to tight regulation. Several differe...

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Bibliographic Details
Published inCurrent opinion in nephrology and hypertension Vol. 6; no. 5; p. 455
Main Authors Muth, T R, Dunbar, L A, Cortois-Coutry, N, Roush, D L, Caplan, M J
Format Journal Article
LanguageEnglish
Published England 01.09.1997
Subjects
Animals
Cell Polarity
Epithelial Cells - cytology
Epithelial Cells - metabolism
Humans
Ion Transport
Proteins - metabolism
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Summary:Transport proteins are targeted to specific plasmalemmal domains in polarized epithelial cells. The molecular signals that govern these sorting events are just beginning to be elucidated. In many cases, the cell surface delivery of transport proteins is subjected to tight regulation. Several different mechanisms appear to participate in these trafficking processes.
ISSN:1062-4821
DOI:10.1097/00041552-199709000-00008