Electroencephalographic and polygraphic features of 24-hour recordings in sleeping sickness and healthy African subjects

Electroencephalographic (EEG) and polygraphic features were analysed in six healthy control subjects and eight patients suffering from sleeping sickness meningoencephalitis in order to determine possible functional relationships. One patient was disqualified because of intermittent metabolic disease...

Full description

Saved in:
Bibliographic Details
Published inJournal of clinical neurophysiology Vol. 13; no. 4; p. 339
Main Authors Tapie, P, Buguet, A, Tabaraud, F, Bogui, P, Doua, F, Bert, J
Format Journal Article
LanguageEnglish
Published United States 01.07.1996
Subjects
Adolescent
Adult
Animals
Cerebral Cortex - physiopathology
Circadian Rhythm - physiology
Cote d'Ivoire
Delta Rhythm
Electroencephalography - instrumentation
Female
Humans
Male
Middle Aged
Polysomnography - instrumentation
Signal Processing, Computer-Assisted - instrumentation
Sleep Stages - physiology
Theta Rhythm
Trypanosoma brucei gambiense
Trypanosomiasis, African - diagnosis
Trypanosomiasis, African - physiopathology
Wakefulness - physiology
Cote d'Ivoire
Online AccessGet more information

Cover

More Information
Summary:Electroencephalographic (EEG) and polygraphic features were analysed in six healthy control subjects and eight patients suffering from sleeping sickness meningoencephalitis in order to determine possible functional relationships. One patient was disqualified because of intermittent metabolic disease. Twenty-four h polygraphic recordings-EEG, electrooculography (EOG), electromyography (EMG), nasal and buccal air flow, chest respiratory movements-were performed continuously both on paper and on cassette tapes. Tapes were played back on paper (paper speed: 15 mm/s). Traces were analyzed for normal and pathologic features, and transient activation phases and paroxysmal hypnopompic hypersynchrony events were counted. During wakefulness, slow theta and delta waves occurred in four patients, but alpha reactivity was present. During sleep, normal features were seen. However, transient activation phases were decreased in the patients. During slow-wave sleep, four patients presented predominantly monophasic frontal delta bursts along with paroxysmal hypnopompic hypersynchrony events. In conclusion, in sleeping sickness patients, although dampened, the waking process remains responsive and slows down only during the late stage of meningoencephalitis.
ISSN:0736-0258
1537-1603
DOI:10.1097/00004691-199607000-00008