The Current Drug Treatment Landscape for Diabetes and Perspectives for the Future

The escalating global epidemic of type 2 diabetes mellitus has focused attention on the devastating consequences of protracted hyperglycemia. Early and effective intervention to control blood glucose is a fundamental principle of treatment guidelines, requiring assiduous use of current therapies. Ho...

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Bibliographic Details
Published inClinical pharmacology and therapeutics Vol. 98; no. 2; p. 170
Main Author Bailey, C J
Format Journal Article
LanguageEnglish
Published United States 01.08.2015
Subjects
Animals
Biomarkers - blood
Blood Glucose - drug effects
Blood Glucose - metabolism
Diabetes Mellitus, Type 2 - blood
Diabetes Mellitus, Type 2 - diagnosis
Diabetes Mellitus, Type 2 - drug therapy
Drug Discovery - trends
Forecasting
Humans
Hypoglycemic Agents - adverse effects
Hypoglycemic Agents - therapeutic use
Molecular Targeted Therapy - trends
Treatment Outcome
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Summary:The escalating global epidemic of type 2 diabetes mellitus has focused attention on the devastating consequences of protracted hyperglycemia. Early and effective intervention to control blood glucose is a fundamental principle of treatment guidelines, requiring assiduous use of current therapies. However, many patients do not achieve or maintain glycemic targets, emphasizing the need for further therapies. This narrative review assesses the available medicinal options to address hyperglycemia and the opportunities to develop novel agents.
ISSN:1532-6535
DOI:10.1002/cpt.144