Association between fibromyalgia and cataract: A database retrospective cohort study

This study was set to investigate whether fibromyalgia increased cataract risk.Fibromyalgia patients were the case group and controls were people who never had a history of fibromyalgia. We estimated the hazard ratio of cataract by Cox proportional-hazards model. The adjusted hazard ratios were obta...

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Bibliographic Details
Published inMedicine (Baltimore) Vol. 100; no. 29; p. e26447
Main Authors Hu, Wei-Syun, Lin, Cheng-Li, Chen, Tung-Sheng
Format Journal Article
LanguageEnglish
Published United States Lippincott Williams & Wilkins 23.07.2021
Subjects
Adult
Aged
Cataract - diagnosis
Cataract - epidemiology
Chi-Square Distribution
Cohort Studies
Correlation of Data
Female
Fibromyalgia - diagnosis
Fibromyalgia - epidemiology
Humans
Incidence
Male
Middle Aged
Observational Study
Proportional Hazards Models
Retrospective Studies
Risk Factors
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ISSN0025-7974
1536-5964
1536-5964
DOI10.1097/MD.0000000000026447

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Summary:This study was set to investigate whether fibromyalgia increased cataract risk.Fibromyalgia patients were the case group and controls were people who never had a history of fibromyalgia. We estimated the hazard ratio of cataract by Cox proportional-hazards model. The adjusted hazard ratios were obtained by controlling variables of age, sex, and comorbidities. Stratification analysis was also performed to ensure the association of fibromyalgia and cataract.We included 6949 participants in each groups. The incidence rate of cataract in patients with fibromyalgia (108.9 per 1000 person-years) was higher than that of control group (58.9 per 1000 person-years). The risk of cataract in fibromyalgia patients was 2.48 (95% confidence interval = 2.34-2.63) times higher than subjects without fibromyalgia.Fibromyalgia is associated with higher risk of cataract.
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ISSN:0025-7974
1536-5964
1536-5964
DOI:10.1097/MD.0000000000026447