Characterization of the Antibiotic GE2270 Complex by Combined Liquid Chromatography and Mass Spectrometry

Components of GE2270 Complex, an antibiotic active against Gram‐positive bacteria and anaerobes, were identified by continuous‐flow fast‐atom bombardment mass spectrometry and by combined liquid chromatography and mass spectrometry under electrospray and thermospray ionization conditions. Electrospr...

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Published inRapid communications in mass spectrometry Vol. 10; no. 4; pp. 409 - 412
Main Authors Colombo, L., Guglielmi, D., Selva, E., Stella, S., Stradi, R., Sottani, C., Zerilli, L. F.
Format Journal Article
LanguageEnglish
Published London Heyden & Son Limited 1996
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Summary:Components of GE2270 Complex, an antibiotic active against Gram‐positive bacteria and anaerobes, were identified by continuous‐flow fast‐atom bombardment mass spectrometry and by combined liquid chromatography and mass spectrometry under electrospray and thermospray ionization conditions. Electrospray ionization seems to be the most suitable technique for the routine analysis of crude extracts of antibiotics from fermentation broths.
Bibliography:ark:/67375/WNG-N4MH0LXQ-Z
ArticleID:RCM504
istex:0C652C8CE2F2C4A41F3289335CAB96ED024BCB58
ISSN:0951-4198
1097-0231
DOI:10.1002/(SICI)1097-0231(19960315)10:4<409::AID-RCM504>3.0.CO;2-F