Key fragmentation patterns of aporphine alkaloids by electrospray ionization with multistage mass spectrometry
This work reports a detailed study of the fragmentations of aporphine alkaloids by electrospray ionization with multistage mass spectrometry (ESI‐MSn) in positive mode. In a first step the loss of the amino group and its substituent is observed. Further steps display the loss of the peripheral group...
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Published in | Rapid communications in mass spectrometry Vol. 18; no. 5; pp. 523 - 528 |
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Main Authors | , , , , |
Format | Journal Article |
Language | English |
Published |
Chichester, UK
John Wiley & Sons, Ltd
01.01.2004
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Subjects | |
Online Access | Get full text |
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Summary: | This work reports a detailed study of the fragmentations of aporphine alkaloids by electrospray ionization with multistage mass spectrometry (ESI‐MSn) in positive mode. In a first step the loss of the amino group and its substituent is observed. Further steps display the loss of the peripheral groups. Losses of methanol and CO are observed if an OH is vicinal to an OCH3 on the aromatic ring. Otherwise the spectra show radical losses of CH3. or CH3O. as the main fragmentations. If a methylenedioxy group is present losses of formaldehyde followed by CO are observed. These fragmentations yield important information on the structures of aporphines. Copyright © 2004 John Wiley & Sons, Ltd. |
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Bibliography: | ArticleID:RCM1343 istex:3CB292BA6B7E6CFE908C60950B156F01E486D5AD ark:/67375/WNG-JMCK5VJZ-8 ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 |
ISSN: | 0951-4198 1097-0231 |
DOI: | 10.1002/rcm.1343 |