Liquid Ionization Mass Spectrometry of Involatile Organic Compounds: Use of a Needle Electrode and Matrix

Metastable argon atoms at atmospheric pressure were used to ionize organic compounds and an emitter for field desorption was used as a sample holder. The effect of electric field, temperature and additives were investigated for involatile compounds like nucleosides. High voltage applied to the emitt...

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Bibliographic Details
Published inJournal of the Mass Spectrometry Society of Japan Vol. 30; no. 4; pp. 313 - 318
Main Authors Kuwabara, Hirofumi, Tsuchiya, Masahiko
Format Journal Article
LanguageEnglish
Published The Mass Spectrometry Society of Japan 1982
Subjects
Atmospheric pressure ionization
Field desorption
Liquid ionization mass spectrometry
Matrix
Nucleosides
Slow atom bombardment
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Summary:Metastable argon atoms at atmospheric pressure were used to ionize organic compounds and an emitter for field desorption was used as a sample holder. The effect of electric field, temperature and additives were investigated for involatile compounds like nucleosides. High voltage applied to the emitter and a matrix increased the abundance of MH+ ions significantly and long-lasting good mass spectra were obtained. A needle emitter was better than a silicon emitter and Nujol (liquid paraffin) as a matrix was better than glycerol for thermolabile compounds having small proton affinities such as guanosine and creatine.
ISSN:1340-8097
1880-4225
DOI:10.5702/massspec.30.313