Two New Phenolic Compounds from Artemisia iwayomogi

Two new phenolic compounds, (Z)‐5′‐hydroxyjasmone 5′‐O‐{6″‐O‐[(E)‐caffeoyl]‐β‐D‐glucopyranoside} (1) and quercetin‐7‐O‐β‐D‐glucuronide methyl ester (2), along with ten known phenolic compounds, 3–12, were isolated from the aerial parts of Artemisia iwayomogi. Their structures were elucidated by spec...

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Bibliographic Details
Published inHelvetica chimica acta Vol. 97; no. 2; pp. 283 - 289
Main Authors Yan, Xi-Tao, Ding, Yan, Li, Wei, Sun, Ya-Nan, Yang, Seo-Young, Koh, Young-Sang, Kim, Young-Ho
Format Journal Article
LanguageEnglish
Published Zürich WILEY-VCH Verlag 01.02.2014
WILEY‐VCH Verlag
Wiley
Wiley Subscription Services, Inc
Subjects
Anti-inflammatory activity
Artemisia iwayomogi
Bone marrow
Chemistry
Chemistry, Multidisciplinary
IL-12 p40
Phenolic compounds
Physical Sciences
Science & Technology
Anti-inflammatory activity
C-13
IL-12 p40
Phenolic compounds
Artemisia iwayomogi
CONSTITUENTS
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Summary:Two new phenolic compounds, (Z)‐5′‐hydroxyjasmone 5′‐O‐{6″‐O‐[(E)‐caffeoyl]‐β‐D‐glucopyranoside} (1) and quercetin‐7‐O‐β‐D‐glucuronide methyl ester (2), along with ten known phenolic compounds, 3–12, were isolated from the aerial parts of Artemisia iwayomogi. Their structures were elucidated by spectroscopic methods, including 1D‐ and 2D‐NMR, and HR‐ESI‐TOF‐MS techniques. The inhibitory effects of compounds 1–12 on the LPS‐stimulated production of IL‐12 p40, IL‐6, and TNF‐α in bone marrow‐derived dendritic cells were evaluated.
Bibliography:ArticleID:HLCA201300170
istex:1BC0F8B31F00A9E268A1719D904F4BE7E77CEB6E
ark:/67375/WNG-0H8BHTCN-S
ISSN:0018-019X
1522-2675
DOI:10.1002/hlca.201300170