Synthesis of pyrrole carboxamide nucleotide triphosphates—putative labelled nucleotide analogues

The syntheses of pyrrole carboxamide nucleotide triphosphates and the initial results of their incorporation by Klenow fragment are reported. The two pyrrole carboxamide nucleotide triphosphates have been prepared and screened as Klenow fragment substrates.

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Published inTetrahedron letters Vol. 43; no. 12; pp. 2289 - 2291
Main Authors Nairne, R.James D., Pickering, Lea, Smith, Clifford L.
Format Journal Article
LanguageEnglish
Published OXFORD Elsevier Ltd 18.03.2002
Elsevier
Subjects
amides
Chemistry
Chemistry, Organic
nucleic acid analogues
nucleotides
Physical Sciences
pyrroles
Science & Technology
amides
pyrroles
nucleotides
nucleic acid analogues
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Abstract The syntheses of pyrrole carboxamide nucleotide triphosphates and the initial results of their incorporation by Klenow fragment are reported. The two pyrrole carboxamide nucleotide triphosphates have been prepared and screened as Klenow fragment substrates.
AbstractList The syntheses of pyrrole carboxamide nucleotide triphosphates and the initial results of their incorporation by Klenow fragment are reported. The two pyrrole carboxamide nucleotide triphosphates have been prepared and screened as Klenow fragment substrates.
The syntheses of pyrrole carboxamide nucleotide triphosphates and the initial results of their incorporation by Klenow fragment are reported. (C) 2002 Elsevier Science Ltd. All rights reserved.
ArticleNumber 0040
Author Pickering, Lea
Nairne, R.James D.
Smith, Clifford L.
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Keywords amides
pyrroles
nucleotides
nucleic acid analogues
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Bergstrom, Zhang, Toma, Andrews, Nicholls (BIB1) 1995; 117
BIB7
BIB4
Nicolaus, Mangoni (BIB6) 1956; 86
BIB3
Jagdmann, Munson, Gero (BIB5) 1990; 20
WOS:000174742700039.1
NICOLAUS RA (WOS:000174742700039.5) 1956; 86
Loakes, D (WOS:000166239400010) 2000; 19
BERGSTROM, DE (WOS:A1995QE73000003) 1995; 117
JAGDMANN, GE (WOS:A1990DK19700015) 1990; 20
Bergstrom (10.1016/S0040-4039(02)00225-3_BIB1) 1995; 117
Nicolaus (10.1016/S0040-4039(02)00225-3_BIB6) 1956; 86
Lakes (10.1016/S0040-4039(02)00225-3_BIB2) 2000; 19
Jagdmann (10.1016/S0040-4039(02)00225-3_BIB5) 1990; 20
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Snippet The syntheses of pyrrole carboxamide nucleotide triphosphates and the initial results of their incorporation by Klenow fragment are reported. The two pyrrole...
The syntheses of pyrrole carboxamide nucleotide triphosphates and the initial results of their incorporation by Klenow fragment are reported. (C) 2002 Elsevier...
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SubjectTerms amides
Chemistry
Chemistry, Organic
nucleic acid analogues
nucleotides
Physical Sciences
pyrroles
Science & Technology
Title Synthesis of pyrrole carboxamide nucleotide triphosphates—putative labelled nucleotide analogues
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