Artemisia annua L. extract ameliorates galactose-induced cognitive impairment in mice

Our previous study showed that Artemisia annua L. extract (AAE) exerted antioxidative effect in a mouse model. Therefore, we hypothesized that AAE could also protect against oxidative stress-induced cognitive impairment, such as memory loss. Oral feeding of an AAE-containing diet resulted in weak ye...

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Bibliographic Details
Published inFood science and biotechnology Vol. 24; no. 5; pp. 1901 - 1905
Main Authors Kim, Mi Hye, Seo, Ji Yeon, Kim, Jong-Sang
Format Journal Article
LanguageEnglish
Published Seoul The Korean Society of Food Science and Technology 01.10.2015
한국식품과학회
Subjects
animal models
antioxidant activity
antioxidants
Artemisia annua
Chemistry
Chemistry and Materials Science
diet
enzymes
Food Science
memory disorders
mice
Nutrition
Research Note
식품과학
cognitive function
Morris water maze task
antioxidant enzymes
Online AccessGet full text
ISSN1226-7708
2092-6456
DOI10.1007/s10068-015-0250-5

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Summary:Our previous study showed that Artemisia annua L. extract (AAE) exerted antioxidative effect in a mouse model. Therefore, we hypothesized that AAE could also protect against oxidative stress-induced cognitive impairment, such as memory loss. Oral feeding of an AAE-containing diet resulted in weak yet significant protection from galactose-induced memory impairment and hippocampal damage in mice. The AAE-induced amelioration was likely associated with the ability of AAE to induce antioxidant enzymes.
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10.1007/s10068-015-0250-5
G704-000139.2015.24.5.039
ISSN:1226-7708
2092-6456
DOI:10.1007/s10068-015-0250-5