A new unique recombinant HIV type 1 isolated from a child born to an HIV-infected mother

• Published in: AIDS research and human retroviruses Vol. 27; no. 12; p. 1323
• Main Authors: Eremin, Vladimir F, Gasich, Elena L, Sasinovich, Sviataslau V
• Format: Journal Article
• Language: English
• Published: United States 01.12.2011
• Subjects: Child; Female; Genes, gag; HIV Infections - transmission; HIV Infections - virology; HIV-1 - classification; HIV-1 - genetics; HIV-1 - isolation & purification; Humans; Infectious Disease Transmission, Vertical; Pregnancy; Pregnancy Complications, Infectious - virology; Recombination, Genetic
• ISSN: 1931-8405
• DOI: 10.1089/aid.2011.0112

The new HIV-1 recombinant, with a B(gag) A(pol)A(env) structure, is described. This recombinant virus differs from the classical "Kaliningrad" (AF193276.1) virus with an A(gag) B(pol)B(env) structure. The number of new HIV cases in Belarus has been increasing in the past few years. Within the 12 months of 2010, 1069 new cases of HIV infection were registered. Molecular epidemiological investigations have shown that though HIV-1 subtype A (84.5%) still dominates in HIV/AIDS patients, the quantity of CRFs has also increased to 7.1%. Although cases with the CRF03_AB virus were previously described in patients from Belarus, CRF06_cpx and CRF02_AG are described in Belarus for the first time.