Photoacoustic tweezers with a pulsed laser: theory and experiments

A novel noninvasive optical technique for manipulating particles and cells is presented that utilizes laser-generated forces in an absorbing medium surrounding the particles or cells. In this technique, a laser pulse creates near-object acoustic waves, which during interaction with the objects lead...

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Bibliographic Details
Published inJournal of physics. D, Applied physics Vol. 38; no. 15; pp. 2662 - 2674
Main Authors Zharov, V P, Malinsky, T V, Kurten, R C
Format Journal Article
LanguageEnglish
Published IOP Publishing 07.08.2005
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Summary:A novel noninvasive optical technique for manipulating particles and cells is presented that utilizes laser-generated forces in an absorbing medium surrounding the particles or cells. In this technique, a laser pulse creates near-object acoustic waves, which during interaction with the objects lead to then being moved or trapped. The main optical schemes are considered, and a theory is presented for this new optical tool, namely photoacoustic (PA) tweezer with pulsed laser. The magnitudes of forces acting on polystyrene particles suspended in water were estimated as a function of the particles' properties for circular and ring geometries of the laser beam. Results of our preliminary experiments demonstrated proof that the manipulation, trapping and even rotation of cells is possible with PA tweezers.
Bibliography:ObjectType-Article-2
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ISSN:0022-3727
1361-6463
DOI:10.1088/0022-3727/38/15/019