A cross-sectional study of the anatomy of the jaws of a central-European caucasian population using cone beam computer tomography as a prerequisite for designing pre-formed calcium phosphate cement scaffolds

• Published in: Annals of anatomy Vol. 254; p. 152270
• Main Authors: Matschke, Jan, Farahzadi, Samaneh, Sembdner, Philipp, Holtzhausen, Stefan, Kroschwald, Lysann, Korn, Paula, Schröder, Tom Alexander, Keil, Christiane, Paetzold-Byhain, Kristin, Lauer, Günter, Franke, Adrian
• Format: Journal Article
• Language: English
• Published: Germany Elsevier GmbH 01.06.2024
• Subjects: Adult; Aged; Aged, 80 and over; Bone Cements; Calcium Phosphates; Calcium-phosphate-cement; CBCT; Cone-Beam Computed Tomography; Cross-Sectional Studies; Female; Humans; Jaw - anatomy & histology; Jaw - diagnostic imaging; Jaw anatomy; Male; Mandible - anatomy & histology; Mandible - diagnostic imaging; Measuring; Middle Aged; Scaffold; Tissue Scaffolds; White People; Young Adult; Calcium-phosphate-cement; Jaw anatomy; Scaffold; Measuring; CBCT
• ISSN: 0940-9602; 1618-0402; 1618-0402
• DOI: 10.1016/j.aanat.2024.152270

This study aims to measure the cortical and cancellous bone thickness in the upper and lower jaws, serving as a data template for developing pre-defined calcium phosphate cement primary implant forms. These measurements are crucial for creating a biphasic scaffold. Forty complete jaws were assessed for cortical bone shape and thickness using statistical analysis and specific software tools. Sex and age were considered, and four groups were created. The cumulative thickness of the cortical layer varied from region to region. In both the upper and lower jaws, the cortical layer in the molar region was significantly thicker than in the frontal region. Within the alveolar process, cortical thickness increases with distance from the alveolar crest on both sides. The oral side of the lower jaw is significantly thicker than the vestibular side. For the upper jaw, no significant differences between the oral and vestibular sides were found in this study. Additionally, it is noteworthy that men have a significantly thicker cortical layer than women. Regarding age, no significant overall differences were found. Mathematical analysis of anatomical forms using polynomial functions improves understanding of jaw anatomy. This approach facilitates the design of patient-specific scaffold structures, minimizing the need for costly and time-consuming planning and enabling more efficient implementation of optimal therapy.