Cerebral and splenic infarctions after injection of N-butyl-2-cyanoacrylate in esophageal variceal bleeding

Variceal bleeding is the most serious complication of portal hypertension, and it accounts for approximately one fifth to one third of all deaths in liver cirrhosis patients. Currently, endoscopic treatment remains the predominant method for the prevention and treatment of variceal bleeding. Endosco...

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Published inWorld journal of gastroenterology : WJG Vol. 19; no. 34; pp. 5759 - 5762
Main Authors Myung, Dae-Seong, Chung, Cho-Yun, Park, Hyung-Chul, Kim, Jong-Sun, Cho, Sung-Bum, Lee, Wan-Sik, Choi, Sung-Kyu, Joo, Young-Eun
Format Journal Article
LanguageEnglish
Published United States Baishideng Publishing Group Co., Limited 14.09.2013
Subjects
Case Report
Cerebral Infarction - etiology
Enbucrilate - administration & dosage
Enbucrilate - adverse effects
Esophageal and Gastric Varices - complications
Esophageal and Gastric Varices - therapy
Female
Gastrointestinal Hemorrhage - etiology
Gastrointestinal Hemorrhage - therapy
Humans
Injections
Middle Aged
Sclerotherapy - adverse effects
Splenic Infarction - etiology
Spleen
Infarction
N-butyl-2-cyanoacrylate
Cerebrum
Esophageal varix
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Summary:Variceal bleeding is the most serious complication of portal hypertension, and it accounts for approximately one fifth to one third of all deaths in liver cirrhosis patients. Currently, endoscopic treatment remains the predominant method for the prevention and treatment of variceal bleeding. Endoscopic treatments include band ligation and injection sclerotherapy. Injection sclerotherapy with N-butyl-2-cyanoacrylate has been successfully used to treat variceal bleeding. Although injection sclerotherapy with N-butyl-2-cyanoacrylate provides effective treatment for variceal bleeding, injection of N-butyl-2-cyanoacrylate is associated with a variety of complications, including systemic embolization. Herein, we report a case of cerebral and splenic infarctions after the injection of N-butyl-2-cyanoacrylate to treat esophageal variceal bleeding.
Bibliography:Telephone: +82-62-2206296 Fax: +82-62-2258578
Correspondence to: Young-Eun Joo, MD, PhD, Department of Internal Medicine, Chonnam National University Medical School, 8 Hak-Dong, Dong-ku, Gwangju 501-757, South Korea. yejoo@chonnam.ac.kr
Author contributions: Myung DS and Joo YE designed the report; Chung CY, Park HC and Kim JS organized the report; Cho SB was the physician for this patient, discussed the treatment plan with the patient, and revised the manuscript; Lee WS and Choi SK provided intellectual advice and revised the manuscript; Myung DS and Joo YE wrote the paper.
ISSN:1007-9327
2219-2840
DOI:10.3748/wjg.v19.i34.5759