Neural Organoids, a Versatile Model for Neuroscience

Three-dimensional cultures of human neural tissue/organlike structures can be achieved by mimicking the developmental processes occurring . Rapid progress in the field of neural organoids has fueled the hope (and hype) for improved understanding of brain development and functions, modeling of neural...

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Bibliographic Details
Published inMolecules and cells Vol. 45; no. 2; pp. 53 - 64
Main Authors Lee, Ju-Hyun, Sun, Woong
Format Journal Article
LanguageEnglish
Published United States Korean Society for Molecular and Cellular Biology 28.02.2022
한국분자세포생물학회
Subjects
Brain
Humans
Minireview
Nervous System Diseases
Organoids
생물학
modeling
human pluripotent stem cells
neurodevelopment
neurological disorders
central nervous system
organoid
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Summary:Three-dimensional cultures of human neural tissue/organlike structures can be achieved by mimicking the developmental processes occurring . Rapid progress in the field of neural organoids has fueled the hope (and hype) for improved understanding of brain development and functions, modeling of neural diseases, discovery of new drugs, and supply of surrogate sources of transplantation. In this short review, we summarize the state-of-the-art applications of this fascinating tool in various research fields and discuss the reality of the technique hoping that the current limitations will soon be overcome by the efforts of ingenious researchers.
Bibliography:https://doi.org/10.14348/molcells.2022.2019
ISSN:1016-8478
0219-1032
DOI:10.14348/molcells.2022.2019