Neurosyphilis presenting as herpes simplex virus encephalitis

A 63‐year‐old woman was admitted to our hospital complaining of sudden slow response and irrelevant answer for three days. The brain magnetic resonance imaging revealed a left‐sided hyperintense lesion and moderate expansiveness involving the hippocampus, insular cortex, and temporal lobe, which mim...

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Published inNeurology and clinical neuroscience Vol. 9; no. 2; pp. 195 - 197
Main Authors Li, Fang‐Zhou, Tian, Jun, Zhang, Yun, Wu, Zhi‐Ying
Format Journal Article
LanguageEnglish
Published Tokyo Wiley Subscription Services, Inc 01.03.2021
Subjects
Agglutination
aging and dementia
Brain diseases
Cerebrospinal fluid
Cortex (insular)
Cortex (temporal)
Encephalitis
Herpes simplex
herpes simplex virus encephalitis
Herpes viruses
imaging
infections/AIDS/Prion Disease
Magnetic resonance imaging
Mimicry
Neuroimaging
Neurosyphilis
Penicillin
Syphilis
Temporal lobe
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Summary:A 63‐year‐old woman was admitted to our hospital complaining of sudden slow response and irrelevant answer for three days. The brain magnetic resonance imaging revealed a left‐sided hyperintense lesion and moderate expansiveness involving the hippocampus, insular cortex, and temporal lobe, which mimicking herpes simplex virus encephalitis. Her cerebrospinal fluid examination disclosed the Treponema pallidum particle agglutination assay and rapid plasma regain test were both positive. A diagnosis of neurosyphilis was made, and the patient was benefited from penicillin therapy.
ISSN:2049-4173
2049-4173
DOI:10.1111/ncn3.12486