A New Entry of Practical and Chemoselective Iodocarbenoids for Carbonyl Iodomethylenation

Direct oxidative addition of CHI3 to the Mg‐TiCl4 bimetallic species resulted in the generation of a highly chemoselective and practically convenient iodomethylenetitanium complex, which efficiently effected condensation even with enolizable or inert carbonyl compounds, such as sterically congested...

Full description

Saved in:
Bibliographic Details
Published inJournal of the Chinese Chemical Society (Taipei) Vol. 64; no. 4; pp. 390 - 394
Main Authors Yan, Tu‐Hsin, Chen, Mei‐Yuan
Format Journal Article
LanguageEnglish
Published Weinheim Wiley‐VCH Verlag GmbH & Co. KGaA 01.04.2017
Wiley
Wiley Subscription Services, Inc
Subjects
Bimetallic species
Carbenoids
Chemistry
Chemistry, Multidisciplinary
Methylenation
Oxidative addition
Physical Sciences
Science & Technology
Vinyl iodide
TANG
Methylenation
RATS
Bimetallic species
Carbenoids
PAEONIFLORIN
MEDICINE
Oxidative addition
RD
GINSENOSIDE RB1
COMPARATIVE PHARMACOKINETICS
MICE
RG1
Vinyl iodide
EXTRACT
Online AccessGet full text

Cover

More Information
Summary:Direct oxidative addition of CHI3 to the Mg‐TiCl4 bimetallic species resulted in the generation of a highly chemoselective and practically convenient iodomethylenetitanium complex, which efficiently effected condensation even with enolizable or inert carbonyl compounds, such as sterically congested ketones, to provide vinyl iodide compounds This Mg‐TiCl4‐promoted CHI‐transfer reaction of CHI3 represents an efficient iodomethylenation of various ketones and aldehyde, especially in enolizable or sterically hindered ketones.
ISSN:0009-4536
2192-6549
DOI:10.1002/jccs.201600875