Vasculitis and Kidney Disease

Pediatric vasculitis is a complex group of disorders that commonly presents with multisystem involvement. Renal vasculitis can be isolated to the kidneys or can occur as part of a broader multiorgan vasculitis. Depending on severity, renal vasculitis may present as acute glomerulonephritis (AGN) oft...

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Bibliographic Details
Published inThe Pediatric clinics of North America Vol. 69; no. 6; p. 1199
Main Authors Grewal, Manpreet K, Adams, Matthew D, Valentini, Rudolph P
Format Journal Article
LanguageEnglish
Published United States 01.12.2022
Subjects
Child
Cognition
Glomerulonephritis - diagnosis
Glomerulonephritis - therapy
Humans
Hypertension
Kidney Diseases - diagnosis
Kidney Diseases - etiology
Kidney Diseases - therapy
Vasculitis - diagnosis
Vasculitis - therapy
Kidney disease
Necrotizing glomerulonephritis
Pediatric vasculitis
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Summary:Pediatric vasculitis is a complex group of disorders that commonly presents with multisystem involvement. Renal vasculitis can be isolated to the kidneys or can occur as part of a broader multiorgan vasculitis. Depending on severity, renal vasculitis may present as acute glomerulonephritis (AGN) often associated with hypertension and sometimes with a rapidly deteriorating clinical course. Prompt diagnosis and initiation of therapy are key to preserving kidney function and preventing long-term morbidity and mortality. This review focuses on the clinical presentation, diagnosis, and treatment objectives for common forms of renal vasculitis seen in pediatric patients.
ISSN:1557-8240
DOI:10.1016/j.pcl.2022.07.009