A sensitive SERS assay for detecting proteins and nucleic acids using a triple-helix molecular switch for cascade signal amplification

A novel surface-enhanced Raman scattering (SERS) detection system is developed for proteins and nucleic acids based on a triple-helix molecular switch for multiple cycle signal amplification, achieving high sensitivity, universality, rapid analysis, and high selectivity.

Saved in:
Bibliographic Details
Published inChemical communications (Cambridge, England) Vol. 50; no. 66; pp. 9409 - 9412
Main Authors Ye, Sujuan, Wu, Yanying, Zhang, Wen, Li, Na, Tang, Bo
Format Journal Article
LanguageEnglish
Published England 25.08.2014
Subjects
Amplification
Cascades
Nucleic acids
Nucleic Acids - analysis
Proteins
Proteins - analysis
Raman scattering
Sensitivity analysis
Spectrum Analysis, Raman - methods
Switches
Systems analysis
Online AccessGet full text

Cover

More Information
Summary:A novel surface-enhanced Raman scattering (SERS) detection system is developed for proteins and nucleic acids based on a triple-helix molecular switch for multiple cycle signal amplification, achieving high sensitivity, universality, rapid analysis, and high selectivity.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:1359-7345
1364-548X
DOI:10.1039/c4cc03988b