Dietary supplementation of organic selenium improves growth, survival, antioxidant and immune status of meagre, Argyrosomus regius, juveniles

• Published in: Fish & shellfish immunology Vol. 68; pp. 516 - 524
• Main Authors: Mansour, Abdallah Tag-Eldein, Goda, Ashraf Abdelsamee, Omar, Eglal Ali, Khalil, Hala Saber, Esteban, Maria Ángeles
• Format: Journal Article
• Language: English
• Published: England Elsevier Ltd 01.09.2017
• Subjects: Animal Feed - analysis; Animals; Antioxidant; Antioxidants - metabolism; Diet - veterinary; Dietary Supplements; Growth; Hematology; Immunity, Innate - physiology; Innate immunity; Liver - enzymology; Liver - metabolism; Longevity; Perciformes - growth & development; Perciformes - immunology; Perciformes - physiology; Random Allocation; Sciaenid fish; Se-yeast; Selenium; Innate immunity; Se-yeast; Sciaenid fish; Hematology; Antioxidant; Growth
• ISSN: 1050-4648; 1095-9947
• DOI: 10.1016/j.fsi.2017.07.060

Oxidative stress is considered one of the main obstacles to immune competence and high mortality rate of marine fish larvae due to the high dietary polyunsaturated fatty acids and accelerated metabolic rate. This study was carried out to assess the effect of different dietary selenium (Se) yeast on growth, antioxidant status, hematological changes, and cellular and humoral immune parameters in meagre (Argyrosomus regius). Juvenile specimens (3.20 ± 0.17 g) were randomly assigned to four experimental groups, a control group fed a basal diet and another three groups fed Se-supplemented diets at doses of 1, 2 and 3 mg Se-yeast kg−1 diet for 63 days and the final analyzed selenium concentrations were 0.77, 1.51, 2.97 and 3.98 mg Se kg−1 diet, respectively. The results indicated that growth performance, feed conversion ratio and survival were significantly improved with 2.97 and 3.98 mg Se-yeast kg−1 compared to the control group. The catalase, superoxide dismutase activities and total antioxidant status were significantly increased, and thiobarbituric reactive substances in liver homogenate were significantly decreased with increasing Se supplementation respect to the control fish in a dose-dependent manner. Furthermore, hematological and innate immune parameters (immunoglobulin, lysozyme, myeloperoxidase, ACH50 and respiratory burst activity) were also significantly higher in fish fed the Se-yeast supplemented diets compared to the control group. The results demonstrated that the supplementation of 3.98 mg Se-yeast kg−1 diet improves growth performance, antioxidant balance and innate immune status of meagre juveniles. [Display omitted] •The high dietary polyunsaturated fatty acids increase oxidative stress risk in marine fish.•The negative effect of increasing reactive oxygen species levels on immune function was confirmed.•Selenium-yeast supplementation alleviated the oxidative stress in meagre fish.•Selenium-yeast supplementation improves hematological, humoral and cellular immune parameters on meagre.