Amyloidosis: a rare cause of severe acute liver failure

Gastrointestinal amyloidosis can be primary, more associated with monoclonal plasma cell dyscrasia, or secondary, usually secondary to a tissue-destructive, chronic inflammatory process (such as inflammatory bowel disease, for example) and long-term dialysis. The rare presentation of severe acute li...

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Published inRevista española de enfermedades digestivas Vol. 116; no. 1; pp. 44 - 45
Main Authors Fernandes, Daniel Alvarenga, Assis-Mendoça, Guilherme Rossi, Costa, Larissa Bastos Eloy da, Freitas, Leandro Luiz Lopes de, Boin, Ilka de Fátima Ferreira Santana, Reis, Fabiano
Format Journal Article
LanguageEnglish
Published Spain 01.01.2024
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Summary:Gastrointestinal amyloidosis can be primary, more associated with monoclonal plasma cell dyscrasia, or secondary, usually secondary to a tissue-destructive, chronic inflammatory process (such as inflammatory bowel disease, for example) and long-term dialysis. The rare presentation of severe acute liver failure in systemic amyloidosis can make this diagnosis/ management more difficult. Hepatomegaly with signs of diffuse infiltrative disease and periportal involvement associated with thoracic and other abdominal radiological findings in the appropriate clinical context may constitute a diagnostic imaging clue in this challenge.
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ISSN:1130-0108
DOI:10.17235/reed.2023.9598/2023