Association of SNPs in miR-146a, miR-196a2, and miR-499 with the risk of endometrial/ovarian cancer

MicroRNAs （miRNAs） are a class of small non-coding RNA molecules （containing N22 nucleotides）, which function in RNA silencing and post-transcriptional regulation of gene expression [1]. miRNAs have been reported to play a key role in tumorigenesis [1], Some single nucleotide polymorphisms （SNPs） in...

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Published inActa biochimica et biophysica Sinica Vol. 47; no. 7; pp. 564 - 566
Main Authors Liu, Xiaoyan, Xu, Beihui, Li, Shujin, Zhang, Bin, Mao, Peimin, Qian, Beibei, Guo, Lin, Ni, Peihua
Format Journal Article
LanguageEnglish
Published China 01.07.2015
Subjects
Case-Control Studies
Endometrial Neoplasms - genetics
Female
Humans
MicroRNAs - genetics
miRNAs
Ovarian Neoplasms - genetics
Polymorphism, Single Nucleotide
RNA沉默
关联性
单核苷酸多态性
卵巢癌
子宫内膜
转录后调控
风险
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Summary:MicroRNAs （miRNAs） are a class of small non-coding RNA molecules （containing N22 nucleotides）, which function in RNA silencing and post-transcriptional regulation of gene expression [1]. miRNAs have been reported to play a key role in tumorigenesis [1], Some single nucleotide polymorphisms （SNPs） in miRNA genes can influence the generation or function of miRNAs, and thereby possibly affect tumor growth and development.
Bibliography:31-1940/Q
MicroRNAs （miRNAs） are a class of small non-coding RNA molecules （containing N22 nucleotides）, which function in RNA silencing and post-transcriptional regulation of gene expression [1]. miRNAs have been reported to play a key role in tumorigenesis [1], Some single nucleotide polymorphisms （SNPs） in miRNA genes can influence the generation or function of miRNAs, and thereby possibly affect tumor growth and development.
ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:1672-9145
1745-7270
DOI:10.1093/abbs/gmv042