Potential action of extract of Acmella oleracea (L.) R.K. Jansen to control Amblyomma cajennense (Fabricius, 1787) (Acari: Ixodidae) ticks

• Published in: Ticks and tick-borne diseases Vol. 8; no. 1; pp. 65 - 72
• Main Authors: Anholeto, Luís Adriano, Oliveira, Patrícia Rosa de, Rodrigues, Rodney Alexandre Ferreira, Spindola, Caroline Dos Santos, Labruna, Marcelo Bahia, Pizano, Marcos Aparecido, Castro, Karina Neoob de Carvaldo, Camargo-Mathias, Maria Izabel
• Format: Journal Article
• Language: English
• Published: Netherlands 01.01.2017
• Subjects: Acaricides - chemistry; Acaricides - pharmacology; Animals; Asteraceae - chemistry; Biological Assay; Female; Ixodidae - drug effects; Male; Plant Components, Aerial - chemistry; Plant Extracts - chemistry; Plant Extracts - pharmacology; Tick Control - methods; Jambu; Acaricide; Natural control; Ticks; LC
• ISSN: 1877-959X; 1877-9603
• DOI: 10.1016/j.ttbdis.2016.09.018

The use of synthetic acaricides is currently the main method to control ticks. However, the indiscriminate use of these chemicals can lead to the selection of resistant individuals and in the accumulation of chemical residues in the environment, contaminating the soil and water streams, consequently affecting the flora, fauna, and the human beings as well. In this sense, the objective of this study was to investigate the acaricidal effect of crude ethanolic extract of Acmella oleracea (L.) R.K. Jansen aerials parts at different concentrations on fed males and semi-engorged females of A. cajennense s.s. An in vitro bioassay (Adult Immersion Test) was carried out to determine the lethal concentration 50 (LC ) of ethanolic extract, calculated by Probit analysis. The results showed that the fed males were sensitive to all the concentrations of A. oleracea ethanolic extract, and mortality rate progressively increased (15-65%) in higher ethanolic extract concentrations. However, semi-engorged females were not sensitive to all the concentrations used here. In the highest concentration (100mg/mL), a mortality rate of 100% was observed after 72h of exposure, indicating that the acaricidal effect would probably be dose-dependent. The LC values obtained for the fed A. cajennense s.s males and semi-engorged females were 29.4534mg/mL (limits: 24.4467-41.3847mg/mL) and LC =17.6335mg/mL (limits: 5.2506-23.5335mg/mL), respectively.