Ultra-high FRET efficiency NaGdF4: Tb3+-Rose Bengal biocompatible nanocomposite for X-ray excited photodynamic therapy application

• Published in: Biomaterials Vol. 184; pp. 31 - 40
• Main Authors: Zhang, Wenli, Zhang, Xiaofeng, Shen, Yingli, Shi, Feng, Song, Chaojun, Liu, Tianshuai, Gao, Peng, Lan, Bin, Liu, Miao, Wang, Sicheng, Fan, Li, Lu, Hongbing
• Format: Journal Article
• Language: English
• Published: Elsevier Ltd 01.11.2018
• Subjects: Antitumor nanocomposite; Deep-seated tumor therapy; FRET; Rear-earth nanoparticles; X-ray excited photodynamic therapy; Deep-seated tumor therapy; X-ray excited photodynamic therapy; FRET; Rear-earth nanoparticles; Antitumor nanocomposite

The limitation of light penetration depth invalidates the application of photodynamic therapy in deep-seated tumors. X-ray excited photodynamic therapy (X-PDT), which is based on X-rays excited luminescent nanoparticles (XLNP), provides a new strategy for PDT in deep tissues. However, the high X-ray...