Prevalence of depressive symptoms in patients with Heart Failure in China: a meta-analysis of comparative studies and epidemiological surveys

• Published in: Journal of affective disorders Vol. 274; pp. 774 - 783
• Main Authors: Lin, Xiao-xiao, Gao, Bei-Bei, Huang, Jin-yu
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier B.V 01.09.2020
• Subjects: China; China - epidemiology; Depression - epidemiology; Depressive symptoms; Female; Heart failure; Heart Failure - epidemiology; Humans; Male; Meta-analysis; Prevalence; Surveys and Questionnaires; China; Heart failure; prevalence; Depressive symptoms; China; Meta-analysis
• ISSN: 0165-0327; 1573-2517
• DOI: 10.1016/j.jad.2020.05.099

•In China, the point prevalence of depression in HF was 43%•In subgroup analyses, the prevalence of depression was higher in females than in males (46% vs 34%, respectively).•Rates of depression were highest when measured using the BDI scale (53.0%) and lowest when measured using the SF-36 scale (24.0%)•The prevalence of depression positively correlated with New York Heart Association functional class (II 28%, III 46%, IV 52%). : Although depressive symptoms is a frequent psychiatric comorbidity in people with Heart Failure (HF) in China, its prevalence was not estimated. This is a meta-analysis of studies examining depressive symptoms in HF patients in China. : The following databases including PubMed, the Cochrace Library, Embase, China National Knowledge Infrastructure (CNKI), WanFang and VIP were independently and systematically searched from inception until March 31, 2019. Statistical analyses were performed using the Stata 13.0 software. The pooled prevalence of depressive symptoms was performed using a random-effects model. In addition, subgroup analysis was conducted based on the New York Heart Association (NYHA) functional class, the assessment tools of depression and gender. : Altogether 53 studies (10649 participants) met the inclusion criteria for the analysis. The point prevalence of depressive symptoms in HF was 43%. In subgroup analyses, the prevalence of depressive symptoms was higher in females than in males (46% vs 34%, respectively), and the prevalence of depressive symptoms positively correlated with New York Heart Association functional classes (II 28%, III 46%, IV 52%) . Rates of depression were highest when measured using BDI scale (62%), and lowest when measured using the CES-D (31%). : This meta-analysis confirmed that the prevalence of depressive symptoms was common in HF patients in China and it is related to the severity of heart failure, gender and the diversity of assessment tools. Appropriate strategies for prevention and treatment of depressive symptoms in this population need greater attention.