Effect of Tissue Inhomogeneity on Nonlinear Propagation of Focused Ultrasound

• Published in: Chinese physics letters Vol. 27; no. 9; pp. 127 - 130
• Main Author: 刘振波 范庭波 郭霞生 章东
• Format: Journal Article
• Language: English
• Published: IOP Publishing 01.09.2010
• Subjects: 不均匀性; 均匀介质; 相关长度; 聚焦能力; 聚焦超声; 非线性传播; 非线性方程
• ISSN: 0256-307X; 1741-3540
• DOI: 10.1088/0256-307X/27/9/094303

We study the influence of tissue inhomogeneity on the focused ultrasound based on the phase screen model and the acoustic nonlinear equation. The inhomogeneous tissue is considered as a combination of a homogeneous medium and a phase aberration screen. Six polyethylene （PE） plates with various correlation lengths and standard deviations are made to mimic the inhomogeneity induced by the human body abdominal. Results indicate that the correlation length affects the side lobe structure of the beam pattern; while the standard deviation is associated with the focusing capability. This study provides a theoretical and experimental basis for the development of a precise treatment plan for high intensity focused ultrasound.