Medical, pharmaceutical, and nutritional applications of 3D-printing technology in diabetes

• Published in: Diabetes & metabolic syndrome clinical research & reviews Vol. 18; no. 4; p. 103002
• Main Authors: Amin, Reza, Hossaeini Marashi, Sayed Mahdi, Reza Noori, Seyyed Mohammad, Alavi, Zeinab, Dehghani, Elaheh, Maleki, Reyhaneh, Safdarian, Mehdi, Rocky, Arash, Berizi, Enayat, Amin Alemohammad, Seyyed Mohammad, Zamanpour, Setayesh, Ali Noori, Seyyed Mohammad
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier Ltd 01.04.2024
• Subjects: 3D printer; Additive manufacturing; diabetes; Nutrition; Personalized medicine; Pharmaceutics; 3D printer; Pharmaceutics; Additive manufacturing; Nutrition; Personalized medicine; diabetes
• ISSN: 1871-4021; 1878-0334; 1878-0334
• DOI: 10.1016/j.dsx.2024.103002

Despite numerous studies covering the various features of three-dimensional printing (3D printing) technology, and its applications in food science and disease treatment, no study has yet been conducted to investigate applying 3D printing in diabetes. Therefore, the present study centers on the utilization and impact of 3D printing technology in relation to the nutritional, pharmaceutical, and medicinal facets of diabetes management. It highlights the latest advancements, and challenges in this field. In this review, the articles focusing on the application and effect of 3D printing technology on medical, pharmaceutical, and nutritional aspects of diabetes management were collected from different databases. High precision of 3D printing in the placement of cells led to accurate anatomic control, and the possibility of bio-printing pancreas and β-cells. Transdermal drug delivery via 3D-printed microneedle (MN) patches was beneficial for the management of diabetes disease. 3D printing supported personalized medicine for Diabetes Mellitus (DM). For instance, it made it possible for pharmaceutical companies to manufacture unique doses of medications for every diabetic patient. Moreover, 3D printing allowed the food industry to produce high-fiber and sugar-free products for the individuals with DM. In summary, applying 3D printing technology for diabetes management is in its early stages, and needs to be matured and developed to be safely used for humans. However, its rapid progress in recent years showed a bright future for the treatment of diabetes. [Display omitted] •3D printing leads to accurate anatomic control and the possibility of bioprinting pancreas and β-cells.•Transdermal drug delivery via 3D-printed microneedle patches was beneficial for the management of diabetes disease.•3D printing was helpful for pharmaceutical industries to produce customized dosage drugs for each diabetic patient.•3D printing allowed the food industries to produce high-fiber and sugar-free products for people with diabetes.