The accuracy of self-reported blood pressure in the Medication adherence Improvement Support App For Engagement–Blood Pressure (MedISAFE-BP) trial: Implications for pragmatic trials

• Published in: The American heart journal Vol. 220; pp. 68 - 72
• Main Authors: Haff, Nancy, Lauffenburger, Julie C., Morawski, Kyle, Ghazinouri, Roya, Noor, Nudrat, Kumar, Shefali, Juusola, Jessie, Choudhry, Niteesh K.
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.02.2020
• Subjects: Age Factors; Blood Pressure; Blood Pressure Determination; Data Accuracy; Exercise; Female; Humans; Hypertension - diagnosis; Logistic Models; Male; Medication Adherence; Middle Aged; Mobile Applications; Patient Selection; Self Report - standards; Self Report - statistics & numerical data; Smartphone; Surveys and Questionnaires - statistics & numerical data
• ISSN: 0002-8703; 1097-6744
• DOI: 10.1016/j.ahj.2019.10.018

Self-report of health conditions and behaviors is one potential strategy to increase the pace of enrollment into pragmatic clinical trials. In this study, we assessed the accuracy of self-reported poorly controlled hypertension among adults in the community who were screened for participation in the MedISAFE-BP trial. Of individuals who self-reported poorly controlled hypertension using the online trial enrollment platform, 64% had a systolic blood pressure less than 140 mm Hg when measured at home. Although we identified several characteristics associated with accurate self-report including older age (odds ratio [OR] 1.02 per year, 95% CI 1.01-1.03), diabetes (OR 1.59, 95% CI 1.17-2.14), and low health activation (OR 1.56 95% CI 1.17-2.07), we were unable to identify patients for whom self-reported hypertension would be a reliable method for their inclusion in a pragmatic trial.