Immunoglobulin binding (B1) domain mediated antibody conjugation to quantum dots for in vitro and in vivo molecular imaging

A facile method for the preparation of antibody-quantum dot (QD) conjugates using the immunoglobulin binding (B1) domain of protein G is presented. The utility of antibody-QD conjugates using the B1 domain is demonstrated for fluorescence imaging of breast tumor cells in vitro and in vivo.

Saved in:
Bibliographic Details
Published inChemical communications (Cambridge, England) Vol. 53; no. 68; pp. 9450 - 9453
Main Authors Tsuboi, Setsuko, Sasaki, Akira, Sakata, Takao, Yasuda, Hidehiro, Jin, Takashi
Format Journal Article
LanguageEnglish
Published England 2017
Online AccessGet full text

Cover

More Information
Summary:A facile method for the preparation of antibody-quantum dot (QD) conjugates using the immunoglobulin binding (B1) domain of protein G is presented. The utility of antibody-QD conjugates using the B1 domain is demonstrated for fluorescence imaging of breast tumor cells in vitro and in vivo.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:1359-7345
1364-548X
DOI:10.1039/c7cc04966h