Inhibitory actions of lupinifolin isolated from Derris reticulata stem against carbohydrate-digesting enzymes

• Published in: Pharmacognosy research Vol. 12; no. 2; pp. 102 - 106
• Main Authors: Pulbutr, Pawitra, Nantana, Pichnatcha, Suksabai, Surabot, Mudjupa, Chawannuch, Denchai, Rattazart, Rattanakiat, Sakulrat, Dhammaraj, Taweesak
• Format: Journal Article
• Language: English
• Published: Bangalore Wolters Kluwer India Pvt. Ltd 01.04.2020; Medknow Publications and Media Pvt. Ltd; Phcog.net
• Subjects: Amylases; Carbohydrates; Diabetes; Diabetes mellitus; Diabetes therapy; Diagnostic imaging; Enzyme kinetics; Glucose; Herbal medicine; Hyperglycemia; Mass spectrometry; Medical research; Medicinal plants; NMR; Nuclear magnetic resonance; Software; Spectroscopy; Statistical analysis; Type 2 diabetes; Thailand; Germany; lupinifolin; α-glucosidase; diabetes mellitus; α-amylase; Derris reticulate

Background: Postprandial hyperglycemia is linked with the development of diabetic complications. Inhibition against the carbohydrate-digesting enzymes, specifically pancreatic α-amylase and intestinal α-glucosidase, delays carbohydrate digestion and subsides postprandial plasma glucose (PPG) levels....