Ten years of contact allergy from acrylic compounds in an occupational dermatology clinic

• Published in: Contact dermatitis Vol. 84; no. 4; pp. 240 - 246
• Main Authors: Aalto‐Korte, Kristiina, Suuronen, Katri
• Format: Journal Article
• Language: English
• Published: Oxford, UK Blackwell Publishing Ltd 01.04.2021; Wiley Subscription Services, Inc
• Subjects: 1,4‐butanedioldimethacrylate (BUDMA); 1,6‐hexanedioldiacrylate (HDDA); Adhesives; Allergies; Contact dermatitis; cyanoacrylate; Dental sealants; dimethylaminoethyl methacrylate (DMAEMA); Eyelid; lash extension glue; Monomers; polyester resin; Sealing compounds; tri(propyleneglycol) diacrylate (TPGDA); urethane diacrylate, aromatic (ar‐UDA); windscreen glue; 1,4-butanedioldimethacrylate (BUDMA); lash extension glue; polyester resin; 1,6-hexanedioldiacrylate (HDDA); tri(propyleneglycol) diacrylate (TPGDA); windscreen glue; dimethylaminoethyl methacrylate (DMAEMA); cyanoacrylate; urethane diacrylate, aromatic (ar-UDA)
• ISSN: 0105-1873; 1600-0536
• DOI: 10.1111/cod.13739

Background Contact allergy from acrylic compounds is a "hot topic". Knowledge on the exact chemical composition of acrylic products is superficial. Aims To retrospectively describe patients with allergic reactions to acrylic compounds. Methods We included patients who had been tested with acrylate patch test series and displayed allergic reactions to at least one acrylic compound. Chemical analyses were often performed when safety data sheets of implicated products failed to reveal acrylic compounds to which the patient tested positive. Results In 2010–2019 a total of 55 patients met the inclusion criteria. Eight cases of allergic contact dermatitis were due to anaerobic sealants, seven to dental products, three to windscreen glues, seven to eyelash glues and/or nail products in the beauty sector, three to UV‐cured printing inks, two to paints/lacquers, and one to polyester resin system. The origin of these contact allergies was occupational with the exception of four beauty sector workers who had developed eyelid symptoms from eyelash extensions glued onto their own eyelashes. We invariably detected methacrylate monomers in 15 chemical analyses of 12 different anaerobic sealants. Conclusions Safety data sheets of anaerobic sealants often lack warnings for skin sensitization, although these products regularly contain sensitizing methacrylates.