Human Immunodeficiency Virus Postexposure Prophylaxis at Ibadan, Nigeria

HIV infection from occupational and nonoccupational exposures can be prevented through risk assessment and management with antiretroviral drug therapy (ART). This study sought to examine the pattern of presentation and outcome of clients who were given postexposure prophylaxis (PEP) at the Universit...

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Published inJournal of the International Association of Physicians in AIDS Care (Chicago, Ill. : 2002) Vol. 9; no. 3; pp. 187 - 190
Main Authors Olowookere, Samuel A., Fatiregun, Akinola Ayoola
Format Journal Article
LanguageEnglish
Published Los Angeles, CA SAGE Publications 01.05.2010
SAGE PUBLICATIONS, INC
Subjects
Adolescent
Adult
Antiretroviral Therapy, Highly Active
Blood-Borne Pathogens
Child
Child, Preschool
Clients
Drug therapy
Drugs
Female
HIV
HIV Infections - prevention & control
Human immunodeficiency virus
Humans
Infectious Disease Transmission, Patient-to-Professional - prevention & control
Male
Middle Aged
Needlestick injuries
Needlestick Injuries - epidemiology
Nigeria - epidemiology
Post-Exposure Prophylaxis
Rape
Rape - statistics & numerical data
Retrospective Studies
Risk assessment
Nigeria
Nigeria, Ibadan
postexposure prophylaxis
needlestick injuries
rape
HIV
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Summary:HIV infection from occupational and nonoccupational exposures can be prevented through risk assessment and management with antiretroviral drug therapy (ART). This study sought to examine the pattern of presentation and outcome of clients who were given postexposure prophylaxis (PEP) at the University College Hospital, Ibadan, Nigeria. A retrospective review of case notes of clients presenting for HIV PEP from January 2005 to December 2006 was carried out. A total of 48 clients with a mean age of 27.9 ± 12.3 years underwent PEP during the period under review. Rape constituted 50% of reasons for PEP, while needle pricks and blood splash into mucous membranes constituted 25% each. Among those who received therapy, 10 (23.8%) could not complete drug therapy because of side effects. Although no client was HIV positive after the recommended 6 months of follow-up, 8 (16.7%) clients did not complete attendance to the clinic during the period.
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ISSN:1545-1097
2325-9574
1557-0886
2325-9582
DOI:10.1177/1545109709359938