Rapid response to treatment with thalidomide in an adolescent with generalized discoid lupus erythematosus

• Published in: Pediatric dermatology Vol. 37; no. 1; pp. 244 - 245
• Main Authors: Tran, Benjamin, Yazdani Abyaneh, Mohammad‐Ali, Wu, Julia
• Format: Journal Article
• Language: English
• Published: United States Wiley Subscription Services, Inc 01.01.2020
• Subjects: Adolescent; alopecia; Anti-Inflammatory Agents - therapeutic use; Case reports; connective tissue disease; Corticosteroids; Discoid lupus erythematosus; Humans; Hydroxychloroquine - therapeutic use; Immunomodulators; Lupus; Lupus Erythematosus, Discoid - drug therapy; Male; Methotrexate; Pediatrics; Retinoids; Skin diseases; systemic therapy; Teenagers; Thalidomide; Thalidomide - therapeutic use; alopecia; thalidomide; systemic therapy; connective tissue disease

Discoid lupus erythematosus (DLE) is the most common variant of cutaneous chronic lupus erythematosus (CLE). Sun protection, topical corticosteroids, and antimalarials constitute the first‐line options for treatment. In refractory cases, alternative antimalarials, methotrexate, retinoids, and thalid...