Rapid response to treatment with thalidomide in an adolescent with generalized discoid lupus erythematosus

Discoid lupus erythematosus (DLE) is the most common variant of cutaneous chronic lupus erythematosus (CLE). Sun protection, topical corticosteroids, and antimalarials constitute the first‐line options for treatment. In refractory cases, alternative antimalarials, methotrexate, retinoids, and thalid...

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Published inPediatric dermatology Vol. 37; no. 1; pp. 244 - 245
Main Authors Tran, Benjamin, Yazdani Abyaneh, Mohammad‐Ali, Wu, Julia
Format Journal Article
LanguageEnglish
Published United States Wiley Subscription Services, Inc 01.01.2020
Subjects
Adolescent
alopecia
Anti-Inflammatory Agents - therapeutic use
Case reports
connective tissue disease
Corticosteroids
Discoid lupus erythematosus
Humans
Hydroxychloroquine - therapeutic use
Immunomodulators
Lupus
Lupus Erythematosus, Discoid - drug therapy
Male
Methotrexate
Pediatrics
Retinoids
Skin diseases
systemic therapy
Teenagers
Thalidomide
Thalidomide - therapeutic use
alopecia
thalidomide
systemic therapy
connective tissue disease
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Summary:Discoid lupus erythematosus (DLE) is the most common variant of cutaneous chronic lupus erythematosus (CLE). Sun protection, topical corticosteroids, and antimalarials constitute the first‐line options for treatment. In refractory cases, alternative antimalarials, methotrexate, retinoids, and thalidomide have been utilized. We present a case of an adolescent patient with generalized DLE responding rapidly to thalidomide.
Bibliography:ObjectType-Case Study-2
SourceType-Scholarly Journals-1
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ISSN:0736-8046
1525-1470
1525-1470
DOI:10.1111/pde.14067